Molecular Response of Skin to Micromachining by Femtosecond Laser

Pulsed lasers at the near infrared (NIR) range have been widely used in dermatology. Ultrashort pulsed picosecond are found with specific ability of very effective activation skin repair and remodeling along significant photodamage. Femtosecond lasers, a shorter pulse width, may be promising alternative to current NIR clinic. In this study, we performed optical micromachining by femtosecond laser 1,030 nm live mice two modes scanning focused direct irradiation unfocused laser. The acute one-day delayed immune molecular responses studied immunofluorescence microscopy sections. Our data shows can activate without any responses. contrast, deep dermis high regulation interleukin. Those results suggest is good potential repairing little or physical damage.